Hypoxia-inducible factors and obstructive sleep apnea
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چکیده
منابع مشابه
Hypoxia Inducible Factor1-alpha Genetic Polymorphism of Obstructive Sleep Apnea
Obstructive sleep apnea syndrome (OSAS) is characterized with recurrent collapse of upper airway during sleep and results in chronic intermittent hypoxia, which leads to activations of transcriptional factors and critical signaling pathways. HIF-1 is a central component of transcriptional factors involved in hypoxia-induced transcription of specific genes. Our oligo-microarray study showed both...
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Background: It has been implicated that obstructive sleep apnea (OSA) is associated with increased risk of cardiovascular disease including stroke, myocardial infarction, coronary artery disease (CAD) and hypertension. The aim of this study was to investigate the correlation between OSA and severity of atherosclerosis assessed by angiography. Methods: This study included 337 patients ...
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Background and Purpose: Sleep breathing disorders have a negative impact on the illness outcome and quality of life in patients with heart failure. This study was conducted to investigate the probability of obstructive sleep apnea in men with heart failure and some related factors. Method: This was a cross-sectional study conducted on 100 male patients with systolic heart failure selected throu...
متن کاملobstructive sleep apnea
sleep apnea, and particularly obstructive sleep apnea, is a common disorder that is characterized by a repetitive, partial or complete cessation of air flow, associated with oxyhemoglobin desaturation and an increased effort to breath. in recent years, orthodontists have been interested and involved in the management of this disorder since it has been shown that oral appliance therapy can be an...
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Introduction: Chronic obstructive pulmonary disease (COPD) patients are at increased risk of sleep-disorders. The concomitant occurrence of COPD and obstructive sleep apnea hypopnea syndrome (OSAHS) is named overlap syndrome. This study aimed to evaluate the severity of OSAHS in overlap syndrome patients.Materials & Methods: This cross-sectional study was conducted on adult patients with forced...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 2020
ISSN: 0021-9738,1558-8238
DOI: 10.1172/jci137560